Halquinol Bolus uses in veterinary

Veterinary Intestinal Antimicrobial (Gut-acting Antimicrobial)

Healquin™ (Halquinol) Bolus contains Halquinol, an antimicrobial that acts primarily within the gastrointestinal lumen. It is intended to support the management of bacterial enteric infections in livestock under veterinary supervision.

Healquin™ is indicated for the management of bacterial enteritis and diarrhea associated with susceptible intestinal bacteria in:
Cattle, buffalo, sheep and goat 

Adult cattle: 1–2 boluses twice daily.

Calves, sheep and goats: ½–1 bolus twice daily.
It may be used as part of an overall treatment plan together with appropriate fluid therapy and supportive care, as directed by a veterinarian.

Metal ion chelation
Halquinol (a mixture of chlorinated hydroxyquinolines) chelates essential metal ions such as Fe²⁺, Zn²⁺, and Cu²⁺.
These metal ions are required as cofactors for many microbial enzymes.
Without them, critical metabolic reactions slow or stop.
Enzyme inhibition
By depriving microorganisms of essential metal ions, Halquinol inhibits several metalloenzymes involved in:
Energy production
DNA synthesis
RNA synthesis
Protein synthesis
This reduces microbial growth and multiplication.
Disruption of cell membrane function
Halquinol alters membrane permeability.
This causes leakage of essential intracellular components and disturbs nutrient transport and ion balance.
Interference with microbial metabolism
The combined effects impair ATP production and other metabolic pathways.
The microorganism can no longer maintain normal cellular functions.
Local intestinal action
Because Halquinol is poorly absorbed from the gastrointestinal tract, it remains in high concentrations within the intestinal lumen.
This allows it to exert its antimicrobial effect where enteric pathogens are located while producing minimal systemic exposure.
Spectrum of activity
Halquinol has activity against susceptible:
Gram-positive bacteria
Gram-negative bacteria
Some fungi and yeasts
Certain protozoa (depending on species and susceptibility)

✓ Acts locally in the intestinal lumen
✓ Easy oral administration
✓ Suitable for cattle, buffalo, calves, sheep and goats
✓ Can be integrated into comprehensive diarrhea management under veterinary guidance
✓ Manufactured to high quality standards

Mob : +91 7358988520

Mail. gkanimalhealthcare@gmail.com

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